Toxicity is very low, the oral 50% lethal dose being 10 000 mg/kg in rats and the maximum tolerated dose being 300 mg/kg in dogs. Moreover, silymarin is devoid of embryotoxic potential.

If you’re looking for the best liver supplements for dogs, we’ve got you covered! Liver problems in dogs can show up as loss ...

The results of most clinical trials with the thistle (Silybum marianum) extract, silymarin, are difficult to interpret because of a variety of reasons: small sample size, variability in type and ...