def design_primers(snp, ref, alt): # Outer primers F_outer = f"ATGCTAGCTAACCT{snp}GTTCC" # Mock sequence R_outer = f"TAGATCGATAGGCT{snp}ACGGT" # Inner primers (allele-specific) F_inner_alt = ...

"These arms directly address whether the addition of immunotherapy to chemoradiation can improve the pCR," he said, noting that the added immunotherapy improved the pCR rate by 13 percentage points.