Methods Two separate multicenter, randomised, double-blind studies were conducted: (1) celecoxib 400 mg/d (n = 147) vs ibuprofen 2400 mg/d (n = 155) or placebo (n = 141) over 10 days, and (2) ...

Celebrex (celecoxib) and ibuprofen are both classified as nonsteroidal anti-inflammatory drugs (NSAIDs). Both are commonly ...

Studies were selected if they were double blind RCTs that compared celecoxib at a licensed therapeutic dose for ≥12 weeks with placebo or another NSAID in patients with active RA or OA. 1 reviewer ...

[15] The annualised incidence rates of upper gastrointestinal ulcer complications alone and combined with symptomatic ulcers for celecoxib versus comparator NSAIDs were 0.76 vs 1.45% (not ...

Medically reviewed by Marissa Sansone, MD Ibuprofen and meloxicam are both nonsteroidal anti-inflammatory drugs (NSAIDs) that ...

The recent findings of a huge study may erase some concerns about a pain reliever that has long been saddled with a worrisome reputation: celecoxib (Celebrex). While all nonsteroidal anti-inflammatory ...

For patients with osteoarthritis and rheumatoid arthritis it shows similar efficacy to conventional NSAIDs ... of celecoxib for relieving post-operative pain, its place in this indication compared ...

Celecoxib (Celebrex) is the only COX-2 inhibitor currently available in the United States and it is available only by prescription. Meloxicam vs. Ibuprofen for Arthritis Pain The FDA has approved ...

The FDA ordered Pfizer to conduct a post-market study of its safety. That study, called PRECISION (Prospective Randomized Evaluation of Celecoxib Integrated Safety vs. Ibuprofen or Naproxen), compared ...

Short-term studies in mice have shown that two drugs, fenofibrate and celecoxib, substantially increased Aβ42 formation. Previous studies have identified select NSAIDs capable of lowering production ...

Conclusion Like dual COX-inhibiting NSAIDs, selective COX-2 inhibitors can induce elevations of systolic and diastolic blood pressure. Rofecoxib produced nearly identical small changes in SBP and DBP ...