Medically reviewed by Daniel Combs, MD Benadryl (diphenhydramine) is an over-the-counter (OTC) antihistamine commonly used to ...

Diphenhydramine can also cause unwanted ... According to Erman, "If you're used to taking the drug to sleep, going without it will make you anxious, and in fact, unable to sleep"-- even though ...

Ibuprofen (solubilized) 200mg, diphenhydramine HCl 25mg ... tranquilizers, or any other sleep-aid.