Excedrin is a popular over-the-counter (OTC) pain-relieving medication brand with two popular formulations: Excedrin Migraine and Excedrin Extra Strength. Both brands contain the same active ...

Acetaminophen 250mg, aspirin 250mg, caffeine 65mg; caplets. May potentiate anticoagulants, hypoglycemics, methotrexate. May antagonize uricosurics. Increased risk of liver toxicity and/or GI bleed ...

Excedrin Extra Strength caplets, Excedrin PM Headache caplets, and Excedrin Tension Headache caplets due to there being holes in the bottom of the bottles. That sounds like a joke but it’s not.