Yamuna Krishnan at the University of Chicago have identified the protein responsible for a key role in how lysosomes work: how calcium ions get into lysosomes. Published in Science Advances ...

Therefore, lysosomes are comparable to recycling plants ... For their experiments, they used a fluorescently-labeled protein that localizes specifically in phagophores and observed the real ...

New research uncovers how declining protein clearance mechanisms with age lead to Alzheimer’s, Parkinson’s, and other ...

Extending beyond SARS-CoV-2, researchers replaced protein-receptor ACE2 with saccharide-receptor sialic acid (SA) and again found potent clearance of influenza A by the lysosomal trap in cell ...

Researchers from the University of Pittsburgh School of Medicine have linked pulmonary arterial hypertension (PAH), a ...

Thus, by the time the protein achieves its final form ... The ER, Golgi apparatus, and lysosomes are all members of a network of membranes, but they are not continuous with one another.

These molecules, upregulated in cancer cells, are excreted through a surprising mechanism—lysosomal exocytosis. Researchers published their results in the Journal of Cell Biology on January 3 ...

A recent study from Tata Institute of Fundamental Research, Mumbai, India has revealed new details about how our cells clean up and recycle waste.

These molecules, upregulated in cancer cells, are excreted through a surprising mechanism—lysosomal exocytosis. Even more fascinating is the intricate relationship between lysosomal exocytosis ...

Determine Tau-induced lysosomal proteome and metabolome changes and test TFEB ... spreading through selective targeting of pathological MAPT (microtubule associated protein Tau). Autophagy 2019; 15(4) ...

The lab also studies mechanisms that regulate autophagy protein and lysosome function in endocytic trafficking and nutrient homeostasis. Figure 1. Entosis promotes cell competition. (A) Entosis ...