For heavy drinkers, chronic pain associated with alcohol withdrawal could be permanent
More information: Vittoria Borgonetti et al, Excessive alcohol intake produces persistent mechanical allodynia and ...
Nature2 j
Endogenous capsaicin-like compounds and hyperalgesia
This previously unknown family of endogenous TRPV1 ligands and their related linoleic acid metabolites were potent activators of TRPV1 and could initiate the development of mechanical allodynia.