Midazolam in combination with neuroleptics was used in one case of sedation maintained until death, while four transitory sedations were induced using ketamine. Opioids were used in 24.4% of cases, ...

Opioid-related neurocognitive symptoms among patients on long-term opioid therapy were most prevalent during the course of ...

Sedation and pain management will be guided using an explicit bedside nurse driven sedation opioid analgesia algorithm. Isoflurane will be infused into the AnaConDa device (Sedana Medical, Uppsala, ...

In this article, we assess the evidence on pain management and sedation strategies in the ICU, the importance of these strategies for patient outcomes in the ICU and after discharge, landmark studies ...

Objectives & Background The safety of intravenous ketamine in procedural sedation is well described. 1 2 Guidelines produced by NICE 3 and the College of Emergency Medicine 4 are used by Emergency ...

Sedation rapid opiate detox treatment is for motivated patients who want to live free of all opiates without substituting Suboxone or Methadone. Acute withdrawals are the main reason why such ...

In this study, we found that 16% of all studied patients required doubling of their opioid dose by 7 days and 20% by 14 days. This outcome was more likely among patients exposed to opioid ...

Melt Pharmaceuticals has reported encouraging topline results from its Phase III trial of MELT-300, a non-intravenous, non-opioid sedation tablet for cataract surgery. The pivotal study's design ...

Introduction Safe and effective sedation and analgesia in children’s critical care is a complex area of medicines use. Analgesia and sedation are needed to treat any pain during a critical care stay, ...

Background Naloxone is an opioid antagonist, indicated for the reversal of central nervous depression and respiratory depression, in the treatment of opioid overdose/intoxication. A National Safety ...