Mendelian randomization is a study design that uses genetic variants as instrumental variables to test the causal effect of a (non-genetic) risk factor on a disease or health-related outcome. Since ...

Mendelian randomization (MR) is an analytical method that statistically infers causal relationships from an exposure to an outcome (disease). It uses genetic variants associated with the exposure as ...

This paper is a practical guide (a toolkit) for researchers, students and practitioners wishing to introduce randomization as part of a research design in the field. It first covers the rationale for ...

Mendelian randomization (MR) represents a valuable methodology to address the causal relationships between an exposure and an outcome. In MR studies, instrumental variables associated with the ...

Researchers from the HIV Prevention Trials Network (HPTN) presented results from the HPTN 094 ("INTEGRA") study at the 2025 ...

Using domain randomization, we repeatedly randomize the simulation dynamics during training in order to learn a good policy under a wide range of physical parameters. IsaacGymEnvs supports "on the fly ...

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Aortic dissection is a life-threatening condition with complex immunological underpinnings. This article ...

A 2‐sample Mendelian randomization approach was applied to assess these associations, while multivariate Mendelian randomization and mediation analyses investigated the role of lipids in mediating the ...

The following is a summary of “Mendelian randomization of plasma proteomics identifies novel ALS-associated proteins and their GO enrichment and KEGG pathway analyses,” published in the March 2025 ...

It contributes to the broader discourse on the potential of hybrid, randomization-inspired neural networks in medical imaging. This fusion of deep learning innovation with the principles of ...