Frizzled (FZD) proteins are the principal receptors of the Wnt signaling pathway. However, whether Wnt ligands induce FZD endocytosis and degradation remains elusive. The transmembrane E3 ubiquitin ...

Molecular evolution is the area of evolutionary biology that studies evolutionary change at the level of the DNA sequence. It includes the study of rates of sequence change, relative importance of ...

Synthetic Notch (SynNotch) receptors can be used to endow cells with custom sense-and-respond capabilities. Here, the authors introduce a fluorescein-binding SynNotch as a versatile tool for ...

Created by Johns Hopkins researchers, EpiScalp could significantly reduce false positives and spare patients from medication side effects, driving restrictions, and other quality-of-life challenges ...

While food fads come and go, the latest research points to a focus on balanced macronutrients from whole foods, rather than a restrictive, all-or-nothing approach.

Learn about the Department of Bioengineering, including our mission, history, facilities, and the innovative field we’re shaping. We are committed to providing high-quality teaching both in and ...

Alpha 1-antitrypsin mitigates salt-sensitive hypertension in juvenile mice by reducing diacylglycerol concentrations and protein kinase C activity in kidney membranes ...

eLife is a non-profit organisation inspired by research funders and led by scientists. Our mission is to help scientists accelerate discovery by operating a platform for research communication that ...

SMM Exclusive: China Metals Output In February And Forecast For March A Super-Large Rare Earth Ore Deposit Discovered in Yunnan, China, Containing Over 470,000 mt of Key Rare Earth Elements Such as Pr ...