Dexamethasone (or just “dex”) is a synthetic glucocorticoid that is generally used for its potent anti-inflammatory effects. It is rapid acting, and is often selected because, unlike most ...

We sought to unravel how two glucocorticoid receptor-activating compounds, dexamethasone and Compound A, influence glucocorticoid receptor levels and how this can be correlated to their gene ...

We report a case of glucocorticoid-induced psychosis after the administration of dexamethasone post-neurosurgical intervention and its evolution with the initiation of chemotherapy. Although initially ...

Dexamethasone is a synthetic glucocorticoid that demonstrates the same anti-inflammatory effects as cortisol. Accordingly, mitogen-stimulated production of pro-inflammatory cytokines such as ...

The low-dose steroid treatment dexamethasone is a major breakthrough in the fight against the deadly virus, UK experts say. The drug is part of the world's biggest trial testing existing ...

Thus the growth inhibition of rabbit articular chondrocytes by dexamethasone did not seem to be related exclusively to an interaction with the glucocorticoid-receptor complexes.

An anti-inflammatory drug called dexamethasone has been hailed as a ground-breaking treatment for hospital patients seriously ill with Covid-19. A UK trial showed the drug could save lives - the ...

Trans-activation of glucocorticoid response elements (GRE ... (EC50 of 298.68 μM in SKGT-4 and 320 μM in HET1A cell lines, 54% and 36% efficacy of dexamethasone 100 nM, respectively, both p<0.05 ...

1981). Tumors that respond well to dexamethasone, such as cerebral metastases, are characterized by high levels of glucocorticoid receptors. Tumors known to respond less favorably, such as ...

A single dose of dexamethasone has been shown to be non-inferior to a 3- or 5-day course of prednisolone in the management of acute asthma in children and has better tolerability and compliance.

This has led to increased concerns about compliance with treatment after discharge. Dexamethasone is suggested as an alternative due to its longer half-life and therefore shorter course, better ...