H2 antihistamines, such as ranitidine, cimetidine, or famotidine, are used to treat gastric hypersecretion ... forms of mastocytosis). Chemotherapy (aggressive systemic mastocytosis).

Systemic mastocytosis (SM) is characterized by an abnormal accumulation of mast cells, a type of immune cell present throughout the body that contributes to allergic and inflammatory responses.