Scientists have a new target to prevent cold sores after University of Virginia School of Medicine researchers discovered an unexpected way the herpes virus re-activates in the body.

Two viruses can cause genital herpes: herpes simplex virus type 1 (HSV-1) and HSV type 2 (HSV-2). HSV-1 tends to cause sores around the mouth (cold sores) and HSV-2 often causes sores on the genitals.

Genital herpes simplex virus (HSV ... Both HSV types 1 (HSV-1) and 2 (HSV-2) are transmitted across epithelial mucosal cells as well as through skin interruptions, and migrate to nerve tissues ...

Herpes simplex virus type 1 (HSV-1) is the type commonly associated with oral herpes (cold sores). Herpes simplex virus type 2 (HSV-2) is the type commonly associated with genital herpes. Even so, HSV ...

4 Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada 5 Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada ...

Herpes simplex virus type 1 (HSV-1 ... All the cells were cultured at 37°C in a humid atmosphere with 5% CO 2. HSV-1 F strain (ATCC, United States) is a gift from the University of Hong Kong and is ...

Herpes simplex virus type 1 (HSV-1) antigen was detected by immunohistochemistry, HSV-1 DNA by in situ hybridisation, and herpes simplex virus nucleocapsids by electronmicroscopy. These clinical and ...

Another time virus (from Patient 2) was recovered separately from ... Among these 17 patients clinical manifestations of herpes simplex occurred in all but 1 after trigeminal sensory-root section ...

Theralase® validates previous University of Manitoba research by demonstrating that RuvidarTM is safe and effective in the ...

Objective Patients with systemic lupus erythematosus (SLE) are susceptible to herpes simplex ... infection (HR=2.29, p=0.049), intravenous steroid pulse therapy (HR=5.32, p<0.001) and daily oral dose ...

More information: Kamal L Nahas et al, Applying 3D correlative structured illumination microscopy and X-ray tomography to characterise herpes simplex virus-1 morphogenesis, eLife (2025).

investigated the roles of herpes simplex virus 1 (HSV-1) structural proteins using correlative cryo ... Strengths: (1) The study presented a novel approach to studying viral assembly in cellulo. (2) ...