It has been used widely to treat other fibrotic ... patients with early chronic disease to receive either 400 mg sustained-release pentoxifylline or placebo twice daily for 6 months.
A double-blind, randomized, six-month study by Roekaerts and Deleers [39] assessed the efficacy and safety of pentoxifylline 400 mg three times daily versus placebo in 36 patients with IC.