Similar to a small cut that heals itself after a short time, individual cells in our body suffer "wounds" in their protective ...

Cell membranes protect and organize cells. All cells have an outer plasma membrane that regulates not only what enters the cell, but also how much of any given substance comes in. Unlike ...

In this diagram of G-protein-coupled receptor activation, the alpha, beta, and gamma subunits are shown with distinct relationships to the plasma membrane. After exchange of GDP with GTP on the ...

Light and electron microscopy have distinct limitations. Light microscopy makes it difficult to resolve smaller and smaller ...

In Gip1-deficient cells, the secretory pathway could not be precisely located due to the defects in regenerating ER exit sites, resulting in the formation of abnormal spore plasma membranes.

The fight against cancer often begins with uncovering hidden players, and this study reveals one such key player: an unexpected class of abbreviated N-glycans. These molecules, upregulated in cancer ...

Lysosomal exocytosis occurs when the lysosomes fuse with the plasma membrane of a cell to expose and release their contents outside of the cell. Essentially, lysosomes and lysosomal exocytosis act ...

Here, we use a synthetic amphiphile to modulate the membrane mechanical properties of cell-derived vesicles and probe channel activation. Using precise membrane mechanical characterization approaches ...

Membrane Tension Regulation is Required for Wound Repair. Adv Sci (Weinh). Institute of Medical Biochemistry ...