Introduction Melatonin has been studied in headache disorders. Amitriptyline is efficacious for migraine prevention, but its unfavourable side effect profile limits its use. Methods A randomised, ...

In the BNF-C, for amitriptyline and gabapentin there is no dosing advice for migraine prophylaxis. Therefore, there was no dosing regimens to compare to and achieved 0% compliance with the BNF-C.

Preventive antimigraine therapy (PAM) should probably not be considered until the headache frequency exceeds ... 1 studies for PAM – propranolol, amitriptyline, topiramate, valproate and gabapentin.

Medically reviewed by Kristie Reed, PharmD Topamax (topiramate) is an anti-seizure medication that may be prescribed to ...