Nearly half of patients with advanced ovarian cancer treated with first-line poly-ADP-ribose polymerase (PARP) inhibitors experienced recurrence in this real-world study, emphasizing the need for ...

As our knowledge about aromatase inhibitors and their side effects has expanded, questions remain unanswered with regards to their influence on cognition. Future study designs evaluating cognitive ...

With the publication of this study, guselkumab is now the third IL-23 inhibitor to meet its primary efficacy endpoint in this population, joining the already approved mirikizumab and risankizumab. 3,4 ...

New research identifies key cellular mechanism driving Alzheimer's disease. ScienceDaily . Retrieved January 20, 2025 from www.sciencedaily.com / releases / 2024 / 12 / 241223135051.htm ...

Selective serotonin reuptake inhibitors, or SSRIs, were the third class or generation of antidepressants developed. They are now the most commonly prescribed antidepressant medications. They are ...

Then, the homogenizer was washed with 700 µL ice-cold nuclei washing buffer (0.04% bovine serum albumin, 0.2 U/µL RiboLock RNase Inhibitor, 500 mM mannitol, 0.1 mM phenylmethanesulfonyl fluoride ...

These next-generation STAT6 inhibitors demonstrate excellent oral bioavailability, cell permeability, and metabolic stability, and do not target STAT6 for degradation. DeepCure expects to select a ...

Cholinesterase inhibitors prevent the breakdown of a type of neurotransmitter called acetylcholine. Doctors may prescribe this medication for certain neurodegenerative diseases, such as Alzheimer ...

Institute of Biostructures and Bioimaging-CNR, via Pietro Castellino 111, 80131 Naples, Italy ...

Table 1. Summary of medical therapy (chemotherapy and aromatase inhibitors) and measurements of cognitive functioning (neuropsychological testing and functional imaging) and potential ...