Objective To compare the efficacy and safety of oral versus intravenous ibuprofen for the pharmacological closure of patent ductus arteriosus (PDA) in less mature preterm infants. Design Prospective, ...

We report the results of a prospective randomised study comparing the effectiveness and the side effects of ibuprofen and indomethacin in the treatment of PDA in preterm infants with RDS. The study ...

Methods Retrospective review over 3 years of patients treated with ibuprofen at a tertiary neonatal unit. Four outcome measures were used; A no further treatment required, B no longer haemodynamically ...