Treating bipolar disorder can be complex, and doctors may prescribe several medications. One way to treat bipolar disorder is with antidepressants, which increase neurotransmitters in the brain.

In some cases, it is also prescribed (but not FDA-approved) to treat acute bipolar depression. Regardless of why you’re taking sertraline, there’s a good chance you’ll encounter side effects ...

Sertraline (as HCl) 20mg/mL ... monitor for clinical worsening or unusual changes. Screen for bipolar disorder, mania, or hypomania. Monitor for serotonin syndrome; discontinue if occurs.